DCR Cancer Research Results

DCR, Disease control rate: Click to Expand ⟱
Source:
Type: clinical outcome

DCR is generally calculated as:
DCR = complete response (CR) + partial response (PR) + stable disease (SD)
Scientific Papers found: Click to Expand⟱
7000- Fuc,    Efficacy of Low-Molecular-Weight Fucoidan as a Supplemental Therapy in Metastatic Colorectal Cancer Patients: A Double-Blind Randomized Controlled Trial
- Trial, CRC, NA
DCR↑, OS∅, PFS∅, ORR∅, AEs∅, QoL∅,
7004- Fuc,    Effectiveness of Fucoidan on Supplemental Therapy in Cancer Patients: A Systematic Review
- Review, Var, NA
OS↑, DCR↑, Inflam↓, fatigue↓,
7061- GamB,    An open-labeled, randomized, multicentered, phase IIa study for advanced cancer treatment by gambogic acid injection (THS)
- Trial, Var, NA
ORR↑, DCR↑, *toxicity↓,
7054- GamB,    An open-labeled, randomized, multicenter phase IIa study of gambogic acid injection for advanced malignant tumors
- Trial, Var, NA
Dose↝, DCR↝,
7990- itraC,    A Novel Approach to Reducing Chemoresistance in Advanced Ovarian Cancer: The Effect of Itraconazole-A Single-Institution Randomized Placebo-Controlled Trial
- Trial, Ovarian, NA
Dose↝, DCR↑, PFS↑, CA125↓, P-gp/ABCB1↓, VEGFR2/KDR/Flk1↑, toxicity↓, QoL↑, toxicity↝,
8126- LF,    Randomized, double-blind, placebo-controlled phase II study of single-agent oral talactoferrin in patients with locally advanced or metastatic non-small-cell lung cancer that progressed after chemotherapy
- NA, NSCLC, NA
Dose↝, OS↑, PFS↑, DCR↑, other↝,

Showing Research Papers: 1 to 6 of 6

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

AEs∅, 1,   DCR↑, 5,   DCR↝, 1,   ORR↑, 1,   ORR∅, 1,   PFS↑, 2,   PFS∅, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

VEGFR2/KDR/Flk1↑, 1,  

Barriers & Transport(tgid=15) ⓘ

P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 3,  

Clinical Biomarkers(tgid=22) ⓘ

CA125↓, 1,  

Functional Outcomes(tgid=23) ⓘ

fatigue↓, 1,   OS↑, 2,   OS∅, 1,   QoL↑, 1,   QoL∅, 1,   toxicity↓, 1,   toxicity↝, 1,  
Total Targets: 20

Pathway results for Effect on Normal Cells:


Functional Outcomes(tgid=23) ⓘ

toxicity↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: DCR, Disease control rate
2 Fucoidan
2 Gambogic Acid
1 itraconazole
1 Lactoferrin/Talactoferrin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1558  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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