Database Query Results : , , JAML

JAML, Junctional Adhesion Molecule-Like: Click to Expand ⟱
Source:
Type:
Major co-stimulatory molecule in epithelial γδ T cells.
A protein that plays a role in cell adhesion and is involved in various biological processes, including immune responses and inflammation.
JAML can influence tumor progression and metastasis by affecting the behavior of immune cells and the tumor microenvironment.
JAML is expressed on certain immune cells, such as T cells and dendritic cells. Its role in immune cell adhesion and migration may affect the infiltration of immune cells into tumors, potentially impacting the effectiveness of anti-tumor immune responses.
Higher or lower levels of JAML expression may correlate with patient outcomes, although findings can vary depending on the type of cancer.

Tumor Suppressive Role: In some contexts, JAML may act as a tumor suppressor by promoting cell adhesion and immune cell interactions, which can enhance anti-tumor immunity.
Tumor Promoting Role: Conversely, in certain tumor microenvironments, JAML may facilitate tumor progression by promoting cell adhesion and migration, potentially aiding in metastasis.

In BC, CRC, and lung cancers low levels generally mean worse prognosis.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: JAML, Junctional Adhesion Molecule-Like
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:167  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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