BronC Cancer Research Results

BronC, Bronchoconstriction/Airway Constriction: Click to Expand ⟱
Source:
Type:

Bronchoconstriction

Aliases: Bronchial Constriction; Airway Constriction

Definition: Bronchoconstriction is narrowing of the airways caused predominantly by contraction of bronchial smooth muscle. It may be triggered by cholinergic signaling, histamine, cysteinyl leukotrienes, allergens, or other stimuli.

Asthma relevance: Bronchoconstriction is a major cause of the reversible airflow obstruction experienced during asthma symptoms and exacerbations.

Direction:
Bronchoconstriction ↑ = adverse
Bronchoconstriction ↓ = beneficial

Typical pathway:
M3 receptor / histamine / leukotrienes / allergen signaling → intracellular Ca2+ ↑ → airway smooth-muscle contraction ↑ → Bronchoconstriction ↑ → Airway Resistance ↑



Scientific Papers found: Click to Expand⟱
Showing Research Papers: 0 to 0 of 0

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: BronC, Bronchoconstriction/Airway Constriction
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1727  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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