| Source: CGL-Driver Genes |
| Type: TSG |
| ASXL1 Epigenetic Regulator, Myeloid Driver, and Prognostic Marker ASXL1 might act as a tumor suppressor in CRC. ASXL1 is a tumor suppressor gene and its downregulation or deletion is expected to confer a growth advantage to cells. ASXL1 expression loss or mutation is primarily associated with hematological malignancies, where it generally indicates a poorer prognosis. Tumor Suppressor Function: ASXL1 is involved in chromatin remodeling and gene regulation, which are critical processes for maintaining normal cellular function and preventing uncontrolled cell growth. When ASXL1 is mutated or its expression is lost, it can lead to dysregulation of gene expression, contributing to tumorigenesis. |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:19 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid