Database Query Results : , , MLH1

MLH1, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli): Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
MLH1 (MutL Homolog 1) is a gene that plays a crucial role in the DNA mismatch repair (MMR) system. This system is responsible for correcting errors that occur during DNA replication.
Mutations or epigenetic changes in the MLH1 gene can lead to a deficiency in the mismatch repair system, which is associated with an increased risk of certain types of cancer.
In many cancers, particularly those associated with Lynch syndrome, MLH1 expression may be lost due to mutations in the gene itself or through epigenetic mechanisms such as promoter methylation.


Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: MLH1, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:193  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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