Database Query Results : , , NF1

NF1, neurofibromin 1: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
The NF1 gene, located on chromosome 17, encodes the neurofibromin protein, which is a tumor suppressor. Neurofibromin plays a critical role in regulating cell growth and differentiation, particularly in the nervous system.
Neurofibromin acts as a tumor suppressor by negatively regulating the Ras signaling pathway. When NF1 is expressed normally, it helps control cell proliferation and survival. Loss or reduction of NF1 expression can lead to increased Ras activity, promoting uncontrolled cell growth and tumorigenesis.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: NF1, neurofibromin 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:215  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page