Database Query Results : , , ATRX

ATRX, alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae): Click to Expand ⟱

Source: CGL-Driver Genes

Type: TSG

ATRX is one of the most frequently mutated tumor suppressor genes in human cancers. ATRX protein is a chromatin remodeler and transcriptional regulator that is essential for normal development. ATRX loss in gliomas has been demonstrated to promote ALT. ATRX absence has also been strongly linked to DNA damage and replicative stress [9]. ATRX loss may occur by mutations, deletions, or gene fusions and correlates with other defined molecular changes such as the ALT phenotype, PDGFRA (platelet-derived growth factor receptor alpha) amplification, and TP53 (tumor protein P53) mutation [10].

Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: ATRX, alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:22  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

Database Query Results : , , ATRX

Pathway results for Effect on Cancer / Diseased Cells:

Pathway results for Effect on Normal Cells:

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