Database Query Results : , , CRM1

CRM1, Nuclear exporter CRM1: Click to Expand ⟱
Source: HalifaxProj(inhibit)
Type:
CRM1 (Chromosome Region Maintenance 1) is a protein that plays a crucial role in the nuclear export of proteins and RNA.
CRM1 can influence the localization of tumor suppressor proteins and oncogenes. For example, the export of tumor suppressor proteins like p53 from the nucleus can lead to reduced tumor suppression, promoting cancer cell growth and survival.
CRM1 is often overexpressed in various types of cancers, including breast cancer, colorectal cancer, and leukemia. This overexpression can correlate with poor prognosis and aggressive tumor behavior.
Many solid and hematologic malignancies show CRM1 overexpression, which correlates with:
-High-grade disease
-Metastatic potential
-Poor prognosis


Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CRM1, Nuclear exporter CRM1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:227  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page