Database Query Results : , , PHF6

PHF6, PHD finger protein 6: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
PHF6 (PHD finger protein 6) is a gene that encodes a protein involved in various cellular processes, including transcriptional regulation and chromatin remodeling.

PHF6 is a gene with tumor-suppressive functions that is frequently altered (usually by loss-of-function mutations or decreased expression) in several hematologic malignancies such as T-ALL and AML. Its inactivation is generally associated with features of aggressive disease and poor prognostic indicators. In solid tumors, more research is necessary to define the exact clinical implications. Overall, a normal PHF6 function appears crucial for proper chromatin regulation and gene expression, and its disruption contributes to oncogenic processes through deregulated transcription and impaired differentiation.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: PHF6, PHD finger protein 6
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:251  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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