Database Query Results : , , SMARCB1

SMARCB1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
SMARCB1, also known as INI1, is a gene that encodes a protein involved in the SWI/SNF chromatin remodeling complex, which plays a crucial role in regulating gene expression and maintaining genomic stability.
In many cancers, particularly malignant rhabdoid tumors (MRTs), SMARCB1 is often found to be deleted or mutated, leading to a complete loss of protein expression. This loss is a hallmark of MRTs and is associated with their aggressive nature.
SMARCB1 functions as a tumor suppressor. Its loss can lead to dysregulation of genes involved in cell cycle control, apoptosis, and differentiation, contributing to uncontrolled cell growth and tumor progression.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SMARCB1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:286  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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