Database Query Results : , , ACVR1B

ACVR1B, activin A receptor, type IB: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
Diseases associated with ACVR1B include Pancreatic Cancer.
Activin A receptor type IB (ACVR1B) is a gene that encodes a signaling protein that functions in growth and differentiation.

The prognostic value of ACVR1B expression can vary:
High Expression: In some cancers, high levels of ACVR1B may be associated with poor prognosis, indicating aggressive tumor behavior.
Low Expression: Conversely, low expression levels may correlate with better outcomes in certain contexts.
Tumor Suppressor Role
In some contexts, ACVR1B has been suggested to have tumor suppressor-like functions:

Inhibition of Proliferation: ACVR1B can mediate growth inhibition in certain cell types, and its activation may lead to apoptosis in response to specific signals.
Regulation of Cell Cycle: It may play a role in regulating the cell cycle, which is a critical aspect of tumor suppression
Oncogenic Role
Conversely, in other contexts, ACVR1B may exhibit oncogenic properties:

Tumor Progression: In some cancers, altered expression of ACVR1B can be associated with tumor progression and metastasis.
Context-Dependent Effects: The effects of ACVR1B can vary based on the presence of other signaling molecules and the specific tumor microenvironment.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: ACVR1B, activin A receptor, type IB
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:3  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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