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| TIMP-2 has been shown to have distinct effects on cancer progression compared to TIMP-1.
Research has suggested that TIMP-2 may have anti-tumor effects in certain types of cancer, including: • Inhibiting tumor growth: TIMP-2 has been shown to inhibit the growth of tumor cells in vitro and in vivo. High levels of TIMP-2 have been associated with better prognosis and improved survival in some cancers. High levels of TIMP-2 have been associated with better prognosis and improved survival in some cancers. High TIMP-2 expression: Breast, Lung, colorectal, Prostrate. Low TIMP-2 expression: Ovarian, Pancreatic, Gastric. |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H1299 |
| 3391- | ART/DHA, | Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug |
| - | Review, | Var, | NA |
| 556- | ART/DHA, | Artemisinins as a novel anti-cancer therapy: Targeting a global cancer pandemic through drug repurposing |
| - | Review, | NA, | NA |
| 3167- | Ash, | Withaferin A Inhibits the Proteasome Activity in Mesothelioma In Vitro and In Vivo |
| - | in-vitro, | MM, | H226 |
| 2606- | Ba, | Baicalein: A review of its anti-cancer effects and mechanisms in Hepatocellular Carcinoma |
| - | Review, | HCC, | NA |
| 2617- | Ba, | Potential of baicalein in the prevention and treatment of cancer: A scientometric analyses based review |
| - | Review, | Var, | NA |
| 2746- | BetA, | Betulinic acid induces apoptosis and inhibits metastasis of human colorectal cancer cells in vitro and in vivo |
| - | in-vitro, | CRC, | HCT116 | - | in-vivo, | CRC, | NA |
| 2742- | BetA, | Betulinic acid impairs metastasis and reduces immunosuppressive cells in breast cancer models |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | BC, | 4T1 | - | in-vitro, | BC, | MCF-7 |
| 2790- | CHr, | Chrysin: Pharmacological and therapeutic properties |
| - | Review, | Var, | NA |
| 3238- | EGCG, | Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications |
| - | Review, | Var, | NA |
| 2914- | LT, | Therapeutic Potential of Luteolin on Cancer |
| - | Review, | Var, | NA |
| 3267- | Lyco, | Lycopene inhibits angiogenesis both in vitro and in vivo by inhibiting MMP-2/uPA system through VEGFR2-mediated PI3K-Akt and ERK/p38 signaling pathways |
| - | in-vitro, | Nor, | HUVECs |
| 4782- | Lyco, | New Insights into Molecular Mechanism behind Anti-Cancer Activities of Lycopene |
| - | Review, | Var, | NA |
| 4788- | Lyco, | Lycopene as a potential anticancer agent: Current evidence on synergism, drug delivery systems and epidemiology (Review) |
| - | Review, | Var, | NA |
| 3745- | MFrot, | MF, | The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease |
| - | Review, | AD, | NA |
| 1807- | NarG, | A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies |
| - | Review, | NA, | NA |
| 3347- | QC, | Recent Advances in Potential Health Benefits of Quercetin |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 3371- | QC, | Quercetin induces MGMT+ glioblastoma cells apoptosis via dual inhibition of Wnt3a/β-Catenin and Akt/NF-κB signaling pathways |
| - | in-vitro, | GBM, | T98G |
| 3079- | RES, | Therapeutic role of resveratrol against hepatocellular carcinoma: A review on its molecular mechanisms of action |
| - | Review, | Var, | NA |
| 3086- | RES, | Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells |
| - | in-vitro, | Pca, | LNCaP | - | in-vitro, | Pca, | PC3 | - | in-vitro, | Pca, | DU145 |
| 3332- | SIL, | Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2 |
| - | in-vitro, | Lung, | A549 |
| 3131- | VitC, | Antioxidant Vitamin C attenuates experimental abdominal aortic aneurysm development in an elastase-induced rat model |
| - | in-vivo, | Nor, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:308 State#:% Dir#:%
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