Database Query Results : , , BRCA2

BRCA2, BReast CAncer gene 2: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
BRCA1 and BRCA2 are tumor suppressor genes, which, when they function normally, keep tumors from forming.
BRCA2 mutations are associated with an increased risk for:
Breast cancer
Ovarian cancer
Melanoma
Pancreatic cancer
Prostate cancer
Scientific Papers found: Click to Expand⟱
735- Bor,    Boric Acid Alters the Expression of DNA Double Break Repair Genes in MCF-7-Derived Breast Cancer Stem Cells
- in-vitro, BC, NA
BRCA1↑, BRCA2↑, ATM↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


DNA Damage & Repair ⓘ

ATM↓, 1,   BRCA1↑, 1,   BRCA2↑, 1,  

Clinical Biomarkers ⓘ

BRCA1↑, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: BRCA2, BReast CAncer gene 2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:33  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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