Database Query Results : , , γδ T-cell activity

γδ T-cell activity, γδ T-cell activity: Click to Expand ⟱
Source: HalifaxProj (promote)
Type:
γδ T-cells are a unique subset of T-cells that play a significant role in the immune response, particularly in the context of cancer. Unlike conventional αβ T-cells, γδ T-cells possess distinct T-cell receptors (TCRs) composed of gamma and delta chains. This unique structure allows them to recognize a wide range of antigens, including those derived from stressed, infected, or transformed cells, making them particularly interesting in cancer immunology.

– In many studies, higher levels or functional anti-tumor γδ T-cell activity (especially IFN-γ producing γδ T cells) have been associated with improved patient outcomes.
– Their capability to recognize and directly kill stressed or transformed cells contributes to tumor immune surveillance.
– γδ T cells can produce pro-inflammatory cytokines (like IFN-γ) that support anti-tumor immune responses.
– Alternatively, in certain microenvironments, they may secrete IL-17 or other factors that could promote tumor-associated inflammation and even angiogenesis.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: γδ T-cell activity, γδ T-cell activity
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:343  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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