Database Query Results : , , NQO2

NQO2, N-ribosyldihydronicotinamide:quinone reductase 2: Click to Expand ⟱

Source:

Type:

Curcumol exhibits synergistic lethal effects with TRAIL on cancer cell by directly targeting quinone oxidoreductase 2 (NQO2) to induce reactive oxygen species, triggering ER stress‐C/EBP homologous protein (CHOP)‐death receptor 5 (DR5) signaling to combat TRAIL‐resistant cancer.

Scientific Papers found: Click to Expand⟱

24-

EGCG,

GEN,

QC,

Targeting CWR22Rv1 prostate cancer cell proliferation and gene expression by combinations of the phytochemicals EGCG, genistein and quercetin

in-vitro,

Pca,

22Rv1

 0.1, 1, 5, 10, 50 uM

NQO1↑, P53↑, NQO2↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

NQO1↑, 1,

Protein Folding & ER Stress ⓘ

NQO2↑, 1,

DNA Damage & Repair ⓘ

P53↑, 1,
Total Targets: 3

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: NQO2, N-ribosyldihydronicotinamide:quinone reductase 2

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells