Database Query Results : , , Id1

Id1, Inhibitor of DNA binding 1(Inhibitor of Differentiation 1): Click to Expand ⟱

Source:

Type: protein

Inhibitor of DNA binding 1(Inhibitor of Differentiation 1)
The inhibitor of DNA binding (Id) proteins are regulators of cell cycle and cell differentiation. Of all Id family proteins, Id1 is mostly linked to tumorigenesis, cellular senescence as well as cell proliferation and survival. Id1 is a stem cell-like gene more than a classical oncogene. Id1 is overexpressed in numerous types of cancers and exerts its promotion effect to these tumors through different pathways.

Scientific Papers found: Click to Expand⟱

1081-

CBDA,

Down-regulation of cyclooxygenase-2 (COX-2) by cannabidiolic acid in human breast cancer cells

in-vitro,

BC,

MDA-MB-231

25uM 48hr

COX2↓, Id1↓, SHARP↑,

154-

CUR,

Curcumin inhibits expression of inhibitor of DNA binding 1 in PC3 cells and xenografts

vitro+vivo,

Pca,

PC3

Id1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:

Core Metabolism/Glycolysis ⓘ

SHARP↑, 1,

Proliferation, Differentiation & Cell State ⓘ

Id1↓, 2,

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,
Total Targets: 3

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: Id1, Inhibitor of DNA binding 1(Inhibitor of Differentiation 1)

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells