Database Query Results : , , MeCP2

MeCP2, Methyl-CpG-Binding Protein 2: Click to Expand ⟱
Source:
Type:
MeCP2 is a nuclear protein that is mainly studied for its role as an epigenetic regulator of gene transcription. MeCP2, while being an epigenetic reader, also plays a role in the development and/or progression of several types of human cancer.

MeCP2 is generally considered protumorigenic due to its role in promoting gene silencing through DNA methylation. By repressing the expression of tumor suppressor genes, MeCP2 can facilitate tumor growth and progression.
Scientific Papers found: Click to Expand⟱
163- CUR,    Epigenetic CpG Demethylation of the Promoter and Reactivation of the Expression of Neurog1 by Curcumin in Prostate LNCaP Cells
- in-vitro, Pca, LNCaP
MeCP2↓, Neurog1↑, HDAC↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Transcription & Epigenetics ⓘ

MeCP2↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

HDAC↓, 1,   Neurog1↑, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: MeCP2, Methyl-CpG-Binding Protein 2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:522  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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