Database Query Results : , , COL9A3

COL9A3, COL9A3: Click to Expand ⟱
Source:
Type: gene
The COL9A3 gene is a type of collagen gene that encodes for the alpha 3 chain of type IX collagen. Type IX collagen is a type of fibril-associated collagen with interrupted triple helices (FACIT) collagen, which is a component of cartilage and other connective tissues.
COL9A3 has been identified as a potential tumor suppressor gene in breast cancer, with reduced expression levels observed in breast cancer tissues.
Scientific Papers found: Click to Expand⟱
439- CUR,    Curcumin suppresses LGR5(+) colorectal cancer stem cells by inducing autophagy and via repressing TFAP2A-mediated ECM pathway
- in-vitro, CRC, LGR5
Apoptosis↑, TumAuto↑, GP1BB↓, COL9A3↓, COMP↓, AGRN↓, ITGB4↓, LAMA5↓, COL2A1↓, ITGB6↓, LGR5↓, TFAP2A↓, ECM/TCF↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Apoptosis↑, 1,  

Transcription & Epigenetics ⓘ

COMP↓, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

Cell Cycle & Senescence ⓘ

TFAP2A↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

LGR5↓, 1,  

Migration ⓘ

AGRN↓, 1,   COL2A1↓, 1,   COL9A3↓, 1,   GP1BB↓, 1,   ITGB4↓, 1,   ITGB6↓, 1,   LAMA5↓, 1,  

Angiogenesis & Vasculature ⓘ

ECM/TCF↓, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: COL9A3, COL9A3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:523  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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