Database Query Results : , , BMD

BMD, bone mineral density: Click to Expand ⟱

Source:

Type:

The Bone Mineral Density (BMD) Test is a diagnostic tool used to measure the density and strength of bones. A bone mineral density (BMD) test measures calcium and other minerals in bone. Cancer treatments, including chemotherapy, hormone therapy, and radiation, can negatively impact bone health and lead to decreased BMD, increasing the risk of osteoporosis and fractures.
Some studies suggest that low BMD may be associated with poorer survival outcomes in certain cancer types, although the relationship can be complex and influenced by various factors.

Scientific Papers found: Click to Expand⟱

4081-

betaCar,

Vitamin A supplementation and risk of skeletal fracture

Study,

NA,

BMD↓,

3516-

Bor,

Boron in wound healing: a comprehensive investigation of its diverse mechanisms

Review,

Wounds,

*Inflam↓, *antiOx↑, *ROS↓, *angioG↑, *COL1↑, *α-SMA↑, *TGF-β↑, *BMD↑, *hepatoP↑, *TNF-α↑, *HSP70/HSPA5↑, *SOD↑, *Catalase↑, *GSH↑, *MDA↓, *TOS↓, *IL6↓, *JAK2↓, *STAT3↓, *AMPK↑, *lipid-P↓, *VEGF↑, *Half-Life↝,

3512-

Bor,

Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake

in-vitro,

Pca,

DU145

TumCP↓, eIF2α↑, ATF4↑, ATF6↑, GADD34↑, CHOP↓, GRP78/BiP↑, GRP94↑, Risk↓, *BMD↑, Ca+2↓, *Half-Life↝, IRE1∅, chemoP↑,

3520-

Bor,

Effect of boron element on photoaging in rats

in-vivo,

NA,

rats

*hepatoP↑, *BMD↑, *COX2↓, *IL8↓, *NF-kB↓, *IL6↓, *TNF-α↓,

696-

Bor,

Nothing Boring About Boron

Review,

Var,

>3mg

upper intake level (UL) of 20 mg/d

*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,

2153-

Ex,

The Impact of Exercise on Cancer Mortality, Recurrence, and Treatment-Related Adverse Effects

Review,

Var,

eff↑, BMD↑, cognitive↑, OS↑, Remission↑, eff↑,

4005-

K+,

Potassium

Review,

Nor,

Review,

Stroke,

*Risk↓, *Dose↝, *Risk↓, *BMD↑, *glucose↓,

4705-

MEL,

Melatonin: beyond circadian regulation - exploring its diverse physiological roles and therapeutic potential

Review,

Nor,

*CLOCK↝, *BMD↑, *cardioP↑, *neuroP↑, *Sleep↑,

2242-

MF,

Electromagnetic stimulation increases mitochondrial function in osteogenic cells and promotes bone fracture repair

in-vitro,

Nor,

2.5G, 5G, 10G, 15G, and 20G

*MMP↑, *Diff↑, *OXPHOS↑, *BMD↑, ATP∅,

2240-

MF,

Pulsed electromagnetic field induces Ca2+-dependent osteoblastogenesis in C3H10T1/2 mesenchymal cells through the Wnt-Ca2+/Wnt-β-catenin signaling pathway

in-vitro,

Nor,

C3H10T1/2

30 Hz, 1 mT, 2 h/day

PEMF output waveform consisted of a 400 kV/m pulsed burst (pulse width 0.2 m s; pulse wait 0.02 m s; burst width 5 m s; burst wait 60 m s; pulse rise 0.3 m s; pulse fall 2.0 m s) repeated at 30 Hz.

*Ca+2↑, *Diff↑, *BMD↑, *Wnt↑, *β-catenin/ZEB1↑, *eff↝,

2238-

MF,

Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects

Review,

Var,

*BMD↑, *VGCC↑, *Ca+2↑, *NO↑, *eff↓,

4348-

MF,

Pulsed electromagnetic field attenuates bone fragility in estrogen-deficient osteoporosis in rats

in-vivo,

ostP,

 (40 Hz and 25 Hzk), intensities (10 mT and 36.4 μT)

*BMD↑,

4349-

MF,

Long-term effect of full-body pulsed electromagnetic field and exercise protocol in the treatment of men with osteopenia or osteoporosis: A randomized placebo-controlled trial

Trial,

ostP,

0.01–15,000 Hz, with sinusoidal, rectangular, multi-resonance, impulse, or sawtooth waveforms, the full-body maximum intensity is 30 gauss (3,000 microTesla)

Ninety-five males with osteopenia or osteoporosis

*BMD↑, *Pain↓, *QoL↑, *toxicity↓, *Dose↝, *Inflam↓,

3471-

MF,

The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment

in-vivo,

Nor,

PEMF with 40 min/day, five days per week

24 Sprague Dawley (SD) rats

*BMD↑, *NLRP3↓, *proCasp1↓, *cl‑Casp1↓, *IL1β↓, *GSDMD↓,

3741-

MF,

Promising application of Pulsed Electromagnetic Fields (PEMFs) in musculoskeletal disorders

Review,

NA,

usually less than 100 Hz and the magnetic flux density is between 0.1 m T and 30 m T.

*eff↑, *BMD↑, *Inflam↓, *PGE2↓, *IL6↓, *IL8↓, *NF-kB↓, *mTOR↝,

4149-

MF,

Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage

Review,

NA,

*other↑, *BDNF↑, *BMPs↑, *BMD↑,

530-

MF,

Low frequency sinusoidal electromagnetic fields promote the osteogenic differentiation of rat bone marrow mesenchymal stem cells by modulating miR-34b-5p/STAC2

in-vivo,

Nor,

15 Hz, 0.4 -1 mT

rat bone marrow mesenchymal stem cells

*miR-34b-5p↓, *ALP↑, *RUNX2↑, *BMP2↑, *OCN↑, *OPN↑, *β-catenin/ZEB1↑, *STAC2↑, *Diff↑, *BMD↑,

193-

MFrot,

MF,

Rotating Magnetic Field Mitigates Ankylosing Spondylitis Targeting Osteocytes and Chondrocytes via Ameliorating Immune Dysfunctions

in-vivo,

Arthritis,

 Ankylosing Spondylitis arthritis:  Mouse model

BMD↑, Cartilage↑, IL17↓, IL22↓, IL23↓, IL28↓, CD4+↓, CD8+↓, LAMB3↑, COL4↓, THBS2↓, ITGA11↓, PPARγ↑, ACAA1↓, PLIN1↓, FABP4↓, PCK1↓, UCP1↓, TNF-α↓,

3535-

MFrot,

MF,

Pulsed Electromagnetic Field Stimulation in Osteogenesis and Chondrogenesis: Signaling Pathways and Therapeutic Implications

Review,

Nor,

*eff↑, *COL2A1↑, *SOX9↑, *Ca+2↑, *FAK↑, *F-actin↑, *Inflam↓, *other↑, *Diff↑, *BMD↑,

2262-

MFrot,

MF,

Effects of 0.4 T Rotating Magnetic Field Exposure on Density, Strength, Calcium and Metabolism of Rat Thigh Bones

in-vivo,

ostP,

0.4T, 8Hz, 30min/day, 30days

Rat

*BMD↑, *eff↓, *ALP↑, *other↑,

4128-

Silicon,

Silicon as Versatile Player in Plant and Human Biology: Overlooked and Poorly Understood

Review,

NA,

*other↑, *BMD↑, *Dose↝, *cognitive↑, *Dose?,

2211-

SK,

Shikonin mitigates ovariectomy-induced bone loss and RANKL-induced osteoclastogenesis via TRAF6-mediated signaling pathways

in-vivo,

ostP,

mice, RANKL-induced

*BMD↑, *p‑NF-kB↓, *p‑p50↓, *p‑p65↓, *p‑ERK↓, *p‑cJun↓, *p‑p38↓,

4542-

SNP,

Silver Nanoparticles (AgNPs): Comprehensive Insights into Bio/Synthesis, Key Influencing Factors, Multifaceted Applications, and Toxicity─A 2024 Update

Review,

NA,

AntiCan↑, DNAdam↑, ATP↓, Apoptosis↑, ROS↓, TumCCA↑, *Bacteria↓, *BMD↑,

2281-

VitK2,

The biological responses of vitamin K2: A comprehensive review

Review,

Var,

*ROS↓, *12LOX↓, *NF-kB↓, *BMD↑, *hepatoP↑, cycD1/CCND1↓, PKCδ↓, STAT3↓, ERK↑, MAPK↓, ROS↑, PI3K↝, Akt↝, Hif1a↝, *neuroP↑,

1818-

VitK2,

New insights on vitamin K biology with relevance to cancer

Review,

Var,

TumCG↓, ChemoSen↑, toxicity∅, OS↑, BMD↑, eff↑, MMP↓, ROS↑, eff↓, ERK↑, JNK↑, p38↑, Cyt‑c↑, Casp↑, ATP↓, lactateProd↑, AMPK↑, Rho↓, TumCG↓, BioAv↑, cardioP↑, Risk↓,

1815-

VitK3,

VitK2,

Vitamin K

Review,

Nor,

*Dose↝, BMD↑,

1761-

WBV,

Low Intensity Vibration Mitigates Tumor Progression and Protect Bone Quantity and Quality in a Murine Model of Myeloma

in-vivo,

Melanoma,

mice

Dose∅, BMD↑, TumCI↓,

1751-

WBV,

Yoda1 Enhanced Low-Magnitude High-Frequency Vibration on Osteocytes in Regulation of MDA-MB-231 Breast Cancer Cell Migration

in-vitro,

BC,

MDA-MB-231

in-vitro,

AML,

RAW264.7

BMD↑, YAP/TEAD↑, TumCG↓, Strength↑, TumCI↓, Fas↑, Ca+2↑,

1754-

WBV,

Vibration Therapy for Cancer-Related Bone Diseases

Review,

Var,

*BMD↑, *toxicity∅, other↓, Dose↝, Dose↑, eff↑, eff↑, eff↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 29

Pathway results for Effect on Cancer / Diseased Cells:

Infection & Microbiome ⓘ

CD8+↓, 1,
Total Targets: 84

Pathway results for Effect on Normal Cells:

NA, unassigned ⓘ

chemoPv↑, 1,

Redox & Oxidative Stress ⓘ

antiOx↑, 1, Catalase↑, 2, GPx↑, 1, GSH↑, 1, lipid-P↓, 1, MDA↓, 1, OXPHOS↑, 1, ROS↓, 2, SAM-e↑, 1, SOD↑, 2, TOS↓, 1,

Mitochondria & Bioenergetics ⓘ

ATP↝, 1, MMP↑, 1,

Core Metabolism/Glycolysis ⓘ

12LOX↓, 1, AMPK↑, 1, glucose↓, 1, NAD↝, 1,

Cell Death ⓘ

BMP2↑, 1, cl‑Casp1↓, 1, proCasp1↓, 1, GSDMD↓, 1, p‑p38↓, 1,

Kinase & Signal Transduction ⓘ

OCN↑, 1, SOX9↑, 1,

Transcription & Epigenetics ⓘ

p‑cJun↓, 1, other↑, 4,

Protein Folding & ER Stress ⓘ

HSP70/HSPA5↑, 1,

Proliferation, Differentiation & Cell State ⓘ

CLOCK↝, 1, Diff↑, 4, p‑ERK↓, 1, mTOR↝, 1, RUNX2↑, 1, STAT3↓, 1, VGCC↑, 1, Wnt↑, 1,

Migration ⓘ

Ca+2↑, 3, Ca+2↝, 1, COL1↑, 1, COL2A1↑, 1, F-actin↑, 1, FAK↑, 1, OPN↑, 1, serineP↓, 1, STAC2↑, 1, TGF-β↑, 1, α-SMA↑, 1, β-catenin/ZEB1↑, 2,

Angiogenesis & Vasculature ⓘ

angioG↑, 1, miR-34b-5p↓, 1, NO↑, 1, VEGF↑, 1,

Immune & Inflammatory Signaling ⓘ

COX2↓, 1, IL1β↓, 1, IL6↓, 3, IL8↓, 2, Inflam↓, 5, JAK2↓, 1, NF-kB↓, 3, p‑NF-kB↓, 1, p‑p50↓, 1, p‑p65↓, 1, PGE2↓, 1, TNF-α↓, 2, TNF-α↑, 1, VitD↑, 1,

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,

Protein Aggregation ⓘ

NLRP3↓, 1,

Hormonal & Nuclear Receptors ⓘ

testos↑, 1,

Drug Metabolism & Resistance ⓘ

Dose?, 1, Dose↑, 1, Dose↝, 5, eff↓, 2, eff↑, 3, eff↝, 1, Half-Life↝, 2, selectivity↑, 1,

Clinical Biomarkers ⓘ

ALP↑, 2, BMD↑, 22, BMPs↑, 2, Calcium↑, 1, hs-CRP↓, 1, IL6↓, 3, Mag↑, 1, VitD↑, 1,

Functional Outcomes ⓘ

cardioP↑, 1, chemoP↑, 1, ChemoSideEff↓, 1, cognitive↑, 2, hepatoP↑, 3, memory↑, 1, neuroP↑, 3, Pain↓, 1, QoL↑, 1, Risk↓, 3, Sleep↑, 1, toxicity↓, 1, toxicity∅, 1,

Infection & Microbiome ⓘ

Bacteria↓, 1,
Total Targets: 99

Scientific Paper Hit Count for: BMD, bone mineral density

12 Magnetic Fields
4 Boron
3 Magnetic Field Rotating
3 Vitamin K2
3 Whole Body Vibration
1 beta-carotene(VitA)
1 Exercise
1 Potassium
1 Melatonin
1 Silicic Acid
1 Shikonin
1 Silver-NanoParticles
1 VitK3,menadione

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:538  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

Database Query Results : , , BMD

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

Mitochondria & Bioenergetics ⓘ

Core Metabolism/Glycolysis ⓘ

Cell Death ⓘ

Transcription & Epigenetics ⓘ

Protein Folding & ER Stress ⓘ

DNA Damage & Repair ⓘ

Cell Cycle & Senescence ⓘ

Proliferation, Differentiation & Cell State ⓘ

Migration ⓘ

Angiogenesis & Vasculature ⓘ

Immune & Inflammatory Signaling ⓘ

Drug Metabolism & Resistance ⓘ

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

Infection & Microbiome ⓘ

Pathway results for Effect on Normal Cells:

NA, unassigned ⓘ

Redox & Oxidative Stress ⓘ

Mitochondria & Bioenergetics ⓘ

Core Metabolism/Glycolysis ⓘ

Cell Death ⓘ

Kinase & Signal Transduction ⓘ

Transcription & Epigenetics ⓘ

Protein Folding & ER Stress ⓘ

Proliferation, Differentiation & Cell State ⓘ

Migration ⓘ

Angiogenesis & Vasculature ⓘ

Immune & Inflammatory Signaling ⓘ

Synaptic & Neurotransmission ⓘ

Protein Aggregation ⓘ

Hormonal & Nuclear Receptors ⓘ

Drug Metabolism & Resistance ⓘ

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

Infection & Microbiome ⓘ

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