Database Query Results : , , Pain

Pain, Pain: Click to Expand ⟱
Source:
Type:
Pain


Scientific Papers found: Click to Expand⟱
5323- ALC,    Preventive Effect of Acetyl-L-carnitine on Oxaliplatin-induced Peripheral Neuropathy
- Trial, Var, NA
Pain↓, NP/CIPN↓,
5427- ASTX,    Astaxanthin and Cancer Chemoprevention
- Review, Var, NA
chemoP↑, AntiCan↑, chemoPv↑, Risk↓, lipid-P↓, Pain↓, BioAv↑, Dose↝,
5370- AV,    The Effect of Aloe Vera Solution on Chemotherapy-Induced Stomatitis in Clients with Lymphoma and Leukemia: A Randomized Controlled Clinical Trial
- Trial, AML, NA
Dose↝, stomatitis↓, Pain↓,
2521- H2,    Oxyhydrogen Gas: A Promising Therapeutic Approach for Lung, Breast and Colorectal Cancer
- Review, CRC, NA - Review, Lung, NA - Review, BC, NA
Inflam↑, ROS↓, ChemoSen↑, p‑PI3K↓, p‑Akt↓, QoL↑, GutMicro↑, chemoP↑, radioP↑, *NRF2↑, *Catalase↑, *GPx↑, *HO-1↑, *SOD↑, *TNF-α↓, *IL4↓, *IL6↓, ChemoSen↑, Appetite↑, cognitive↑, Pain↓, Sleep↑, other?,
2871- HNK,    Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling
- in-vivo, Nor, NA
*TNF-α↓, *IL1β↓, *IL6↓, *VEGF↓, *NRF2↑, *SOD2↑, *HO-1↑, *Inflam↓, *Pain↓, *NO↓, toxicity↓,
1272- LA,    Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults
- Trial, Nor, NA
*Pain↓, *other↑,
192- MF,    The use of magnetic fields in treatment of patients with rheumatoid arthritis. Review of the literature
- Review, Arthritis, NA
*Dose↝, Pain↓, Inflam↓, Sleep↑,
505- MF,    Amplitude-modulated electromagnetic fields for the treatment of cancer: Discovery of tumor-specific frequencies and assessment of a novel therapeutic approach
- Case Report, NA, NA
Pain↓, OS↑,
4111- MF,    Coupling of pulsed electromagnetic fields (PEMF) therapy to molecular grounds of the cell
- Review, Arthritis, NA
*Inflam↓, *Cartilage↑, *Pain↓, *QoL↑, *Dose↝, *VEGF↑, *NO↑, *TGF-β↑, *MMP9↓, *PGE2↑, *GPx3↑, *SOD2↑, *Catalase↑, *GSR↑, *Ca+2↑,
3566- MF,    Positive and Negative Effects of Administering a Magnetic Field to Patients with Rheumatoid Arthritis (RA)
- Study, Arthritis, NA
*Inflam↓, *QoL↑, *Pain↓, *motorD↑, *toxicity↓, *Cartilage↑, *Inflam↓,
3568- MF,    The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis
- Review, Arthritis, NA
*eff↑, *Pain↓, *motorD↑,
3569- MF,    Current Evidence Using Pulsed Electromagnetic Fields in Osteoarthritis: A Systematic Review
- Review, Arthritis, NA
*Pain↓, *QoL↑, *motorD↑,
4349- MF,    Long-term effect of full-body pulsed electromagnetic field and exercise protocol in the treatment of men with osteopenia or osteoporosis: A randomized placebo-controlled trial
- Trial, ostP, NA
*BMD↑, *Pain↓, *QoL↑, *toxicity↓, *Dose↝, *Inflam↓,
224- MFrot,  MF,    A pilot study of extremely low-frequency magnetic fields in advanced non-small cell lung cancer: Effects on survival and palliation of general symptoms
- Human, NSCLC, NA
PleEff↓, breath↑, Pain↓, Appetite↑, Strength↑, BowelM↑, OS↑,
198- MFrot,  MF,    Biological effects of rotating magnetic field: A review from 1969 to 2021
- Review, Var, NA
AntiCan↑, breath↑, Pain↓, Appetite↑, Strength↑, BowelM↑, TumMeta↓, TumCCA↑, ETC↓, MMP↓, TumCD↑, selectivity↑, ROS↑, Casp3↑, TumCG↓, TumCCA↑, ChrMod↑, TumMeta↓, Imm↑, DCells↑, Akt↓, OS⇅, toxicity↓, QoL↑, hepatoP↑, Pain↓, Weight↑, Strength↑, Sleep↑, IL6↓, CD4+↑, CD8+↑, Ca+2↑, radioP↑, chemoP↑, *BMD↑, *AntiAge↑, *AMPK↑, *P21↓, *P53↓, *mTOR↓, *OS↑, *β-Endo↑, *5HT↓,
217- MFrot,  MF,    Effect of low-frequency rotary magnetic fields on advanced gastric cancer
- in-vivo, GC, HL-60 - in-vivo, GC, SK-HEP-1
OS↑, Pain↓, ChemoSideEff↓, Weight↑, Strength↑, Sleep↑,
3847- MSM,    Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement
- Review, Arthritis, NA
*Inflam↓, *Pain↓, *ROS↓, *antiOx↑, *Dose↝, *Half-Life↝, *NF-kB↓, *IL1↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2↓, *NLRP3↓, *NRF2↑, *STAT↓, *Cartilage↑, *eff↑, *eff↑, *GSH↑, *uricA↓, tumCV↓, TumCCA↑, necrosis↑, Apoptosis↑, VEGF↓, HSP90↓, IGF-1?,
3851- MSM,    Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial
- Trial, Arthritis, NA
*Pain↓, *QoL↑,
2- MushShi,    The Effects of Active Hexose Correlated Compound (AHCC) on Levels of CD4+ and CD8+ in Patients with Epithelial Ovarian Cancer or Peritoneal Cancer Receiving Platinum Based Chemotherapy
- Human, Ovarian, NA
CD8+↑, Pain↑,
3249- PBG,    Can Propolis Be a Useful Adjuvant in Brain and Neurological Disorders and Injuries? A Systematic Scoping Review of the Latest Experimental Evidence
- Review, Var, NA
*Inflam↓, *ROS↓, *MDA↓, *TNF-α↓, *NO↓, *iNOS↓, *SOD↑, *GPx↑, *GSR↓, *GSH↑, *neuroP↑, *IL6↓, *MMP2↓, *MMP9↓, *MCP1↓, *HSP70/HSPA5↑, *motorD↑, *Pain↓, *VCAM-1↓, *NF-kB↓, *MAPK↓, *JNK↓, *IL1β↓, *AChE↓, *toxicity∅, cognitive↑,
3606- QC,    The Effect of Quercetin on Inflammatory Factors and Clinical Symptoms in Women with Rheumatoid Arthritis: A Double-Blind, Randomized Controlled Trial
- Trial, Arthritis, NA
*motorD↑, *Pain↓, *TNF-α↓, *IL8↓, *IL6↓, *IL1β↓, *NF-kB↓, *p38↓,
3343- QC,    Quercetin, a Flavonoid with Great Pharmacological Capacity
- Review, Var, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *angioG↓, *Inflam↓, *BioAv↓, *Half-Life↑, *GSH↑, *SOD↑, *Catalase↑, *Nrf1↑, *BP↓, *cardioP↑, *IL10↓, *TNF-α↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroP↑, *Pain↓, *COX2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL17↓, *MCP1↓, PKCδ↓, ERK↓, BAX↓, cMyc↓, KRAS↓, ROS↓, selectivity↑, tumCV↓, Apoptosis↑, TumCCA↑, eff↑, P-gp↓, eff↑, eff↑, eff↑, eff↑, CycB/CCNB1↓, CDK1↓, CDK4↓, CDK2↓, TOP2↓, Cyt‑c↑, cl‑PARP↑, MMP↓, HSP70/HSPA5↓, HSP90↓, MDM2↓, RAS↓, eff↑,
4754- Se,  Chemo,    The effect of selenium yeast in the prevention of adverse reactions related to platinum-based combination therapy in patients with malignant tumors
- Trial, Var, NA
chemoP↑, QoL↑, chemoP↑, Pain↓,
4742- SSE,    Antitumor Effects of Selenium
- Review, Var, NA - Review, Arthritis, NA - Review, Sepsis, NA
*antiOx↓, *Inflam↓, Risk↓, TumCI↓, TumMeta↓, radioP↑, chemoP↑, Apoptosis↑, ROS↑, DNAdam↑, Dose↑, selectivity↑, *other↓, *BioAv↑, ROS↑, MMP↓, Casp↑, *Imm↑, *Pain↓, Sepsis↓, MMP2↓, MMP9↓, *Half-Life↓,
5078- SSE,  Rad,    Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer
- Trial, Pca, NA
Half-Life↝, OS↑, Pain↓, PSA↓, GSH↓, ROS↑, selectivity↑, TumCG↓, AR↓, Dose↑, ChemoSen↑, RadioS↑,
625- VitC,    The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review
OS↑, Pain↓,
1753- WBV,  Ex,    Physical Exercise with or without Whole-Body Vibration in Breast Cancer Patients Suffering from Aromatase Inhibitor—Induced Musculoskeletal Symptoms: A Pilot Randomized Clinical Study
- Trial, BC, NA
Pain↓, Strength↑, QoL↑, Dose∅,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 27

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned

NP/CIPN↓, 1,   stomatitis↓, 1,  

Redox & Oxidative Stress

GSH↓, 1,   lipid-P↓, 1,   ROS↓, 2,   ROS↑, 4,  

Mitochondria & Bioenergetics

ETC↓, 1,   MMP↓, 3,   PleEff↓, 1,  

Core Metabolism/Glycolysis

cMyc↓, 1,  

Cell Death

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↑, 3,   BAX↓, 1,   Casp↑, 1,   Casp3↑, 1,   Cyt‑c↑, 1,   MDM2↓, 1,   necrosis↑, 1,   TumCD↑, 1,  

Transcription & Epigenetics

BowelM↑, 2,   ChrMod↑, 1,   other?, 1,   tumCV↓, 2,  

Protein Folding & ER Stress

HSP70/HSPA5↓, 1,   HSP90↓, 2,  

DNA Damage & Repair

DNAdam↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence

CDK1↓, 1,   CDK2↓, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State

ERK↓, 1,   IGF-1?, 1,   p‑PI3K↓, 1,   RAS↓, 1,   TOP2↓, 1,   TumCG↓, 2,  

Migration

Ca+2↑, 1,   KRAS↓, 1,   MMP2↓, 1,   MMP9↓, 1,   PKCδ↓, 1,   TumCI↓, 1,   TumMeta↓, 3,  

Angiogenesis & Vasculature

VEGF↓, 1,  

Barriers & Transport

P-gp↓, 1,  

Immune & Inflammatory Signaling

CD4+↑, 1,   DCells↑, 1,   IL6↓, 1,   Imm↑, 1,   Inflam↓, 1,   Inflam↑, 1,   PSA↓, 1,  

Hormonal & Nuclear Receptors

AR↓, 1,  

Drug Metabolism & Resistance

BioAv↑, 1,   ChemoSen↑, 3,   Dose↑, 2,   Dose↝, 2,   Dose∅, 1,   eff↑, 6,   Half-Life↝, 1,   RadioS↑, 1,   selectivity↑, 4,  

Clinical Biomarkers

AR↓, 1,   GutMicro↑, 1,   IL6↓, 1,   KRAS↓, 1,   PSA↓, 1,  

Functional Outcomes

AntiCan↑, 2,   Appetite↑, 3,   breath↑, 2,   chemoP↑, 6,   chemoPv↑, 1,   ChemoSideEff↓, 1,   cognitive↑, 2,   hepatoP↑, 1,   OS↑, 5,   OS⇅, 1,   Pain↓, 14,   Pain↑, 1,   QoL↑, 4,   radioP↑, 3,   Risk↓, 2,   Sleep↑, 4,   Strength↑, 5,   toxicity↓, 2,   Weight↑, 2,  

Infection & Microbiome

CD8+↑, 2,   Sepsis↓, 1,  
Total Targets: 91

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↓, 1,   antiOx↑, 2,   Catalase↑, 3,   GPx↑, 2,   GPx3↑, 1,   GSH↑, 3,   GSR↓, 1,   GSR↑, 1,   HO-1↑, 3,   MDA↓, 1,   Nrf1↑, 1,   NRF2↑, 4,   ROS↓, 3,   SOD↑, 3,   SOD2↑, 2,   uricA↓, 1,  

Core Metabolism/Glycolysis

AMPK↑, 1,  

Cell Death

iNOS↓, 2,   JNK↓, 1,   MAPK↓, 1,   p38↓, 1,  

Transcription & Epigenetics

other↓, 1,   other↑, 1,  

Protein Folding & ER Stress

HSP70/HSPA5↑, 1,  

DNA Damage & Repair

P53↓, 1,  

Cell Cycle & Senescence

P21↓, 1,  

Proliferation, Differentiation & Cell State

GSK‐3β↓, 1,   mTOR↓, 1,   STAT↓, 1,  

Migration

Ca+2↑, 1,   Cartilage↑, 3,   MMP2↓, 1,   MMP9↓, 2,   TGF-β↑, 1,   VCAM-1↓, 1,   β-Endo↑, 1,  

Angiogenesis & Vasculature

angioG↓, 1,   NO↓, 2,   NO↑, 1,   VEGF↓, 1,   VEGF↑, 1,  

Immune & Inflammatory Signaling

COX2↓, 2,   IL1↓, 1,   IL10↓, 1,   IL17↓, 1,   IL1β↓, 4,   IL4↓, 1,   IL6↓, 5,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 9,   MCP1↓, 2,   NF-kB↓, 3,   PGE2↑, 1,   TNF-α↓, 6,  

Synaptic & Neurotransmission

5HT↓, 1,   AChE↓, 1,   tau↓, 1,  

Protein Aggregation

Aβ↓, 1,   NLRP3↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,   BioAv↑, 1,   Dose↝, 4,   eff↑, 3,   Half-Life↓, 1,   Half-Life↑, 1,   Half-Life↝, 1,  

Clinical Biomarkers

BMD↑, 2,   BP↓, 1,   IL6↓, 5,  

Functional Outcomes

AntiAge↑, 1,   cardioP↑, 1,   motorD↑, 5,   neuroP↑, 2,   OS↑, 1,   Pain↓, 13,   QoL↑, 5,   toxicity↓, 2,   toxicity∅, 1,  
Total Targets: 79

Scientific Paper Hit Count for: Pain, Pain
10 Magnetic Fields
3 Magnetic Field Rotating
2 Methylsulfonylmethane
2 Quercetin
2 Selenite (Sodium)
1 Acetyl-l-carnitine
1 Astaxanthin
1 Aloe anthraquinones
1 Hydrogen Gas
1 Honokiol
1 Lactobacillus
1 Mushroom Shiitake, AHCC
1 Propolis -bee glue
1 Selenium
1 Chemotherapy
1 Radiotherapy/Radiation
1 Vitamin C (Ascorbic Acid)
1 Whole Body Vibration
1 Exercise
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:576  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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