Database Query Results : , , HDL

HDL, HDL cholesterol: Click to Expand ⟱
Source:
Type:
High-density lipoprotein (HDL) cholesterol is often referred to as "good" cholesterol because it helps transport cholesterol away from the arteries and back to the liver, where it can be processed and removed from the body.
Some research suggests that higher levels of HDL cholesterol may be associated with a lower risk of certain types of cancer. This could be due to HDL's role in reducing inflammation and oxidative stress, both of which are linked to cancer development.
Other studies have indicated that very high levels of HDL cholesterol might be associated with an increased risk of certain cancers.
While higher levels of HDL cholesterol are generally associated with cardiovascular health and may have protective effects against certain cancers, the evidence is mixed, and the implications for cancer risk and prognosis vary by cancer type.
Scientific Papers found: Click to Expand⟱
3972- ACNs,    Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
- Review, AD, NA - Review, Park, NA
*cardioP↑, *neuroP↑, *Inflam↓, *antiOx↓, *GutMicro↑, *Half-Life↑, *LDL↓, *adiP↓, *HDL↑, *CRP↓, *IL1β↓, *Risk↓, *Risk↓, *cognitive↑, *memory↑, *other↑, *BOLD↑, *NO↓, *MDA↓, *GSH↑, *VitC↑, *SOD↑, *GPx↑, *eff↓, *eff↓, *eff↓, *eff↝, *Risk↓,
759- Bor,    The nutritional and metabolic effects of boron in humans and animals
- in-vivo, NA, NA
DHT↑, VitD↑, HDL↓,
2784- CHr,    Chrysin targets aberrant molecular signatures and pathways in carcinogenesis (Review)
- Review, Var, NA
Apoptosis↑, TumCMig↓, *toxicity↝, ChemoSen↑, *BioAv↓, Dose↝, neuroP↑, *P450↓, *ROS↓, *HDL↑, *GSTs↑, *SOD↑, *Catalase↑, *MAPK↓, *NF-kB↓, *PTEN↑, *VEGF↑, ROS↑, MMP↓, Ca+2↑, selectivity↑, PCNA↓, Twist↓, EMT↓, CDKN1C↑, p‑STAT3↑, MMP2↓, MMP9↓, eff↑, cycD1/CCND1↓, hTERT/TERT↓, CLDN1↓, TumVol↓, OS↑, COX2↓, eff↑, CDK2↓, CDK4↓, selectivity↑, TumCCA↑, E-cadherin↑, HK2↓, HDAC↓,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *eff↑, *LDL↓, *HDL↑, *eff↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
4254- EA,    Chronic administration of ellagic acid improved the cognition in middle-aged overweight men
- Human, Obesity, NA
*LDL↓, *HDL↑, *BDNF↑, *cognitive↑,
1791- LEC,    Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention
- Review, Nor, NA
*BioEnh↑, *antiOx↑, *BioEnh↑, *LDL↓, *HDL∅, *Obesity↓, eff↑, GutMicro↝,
4446- Se,    Antioxidant and Hepatoprotective Effects of Moringa oleifera-mediated Selenium Nanoparticles in Diabetic Rats.
- in-vivo, Diabetic, NA
*glucose↓, *antiOx↑, *GPx↑, *Catalase↑, *SOD↑, *ROS↓, *cardioP↑, *HDL↑, *LDL↓, *hepatoP↑, *TNF-α↓, *IL6↓, *IL1β↓, *lipid-P↓, *Inflam↓, *ALAT↓, *AST↓, *ALP↓, *Dose↝, *Dose↝,
4336- VitB5,    Effectiveness of long-term treatment with pantethine in patients with dyslipidemia
- Trial, NA, NA
*LDL↓, *HDL↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

HDL↓, 1,   ROS↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,  

Core Metabolism/Glycolysis ⓘ

HK2↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   hTERT/TERT↓, 1,  

DNA Damage & Repair ⓘ

PCNA↓, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,   HDAC↓, 1,   p‑STAT3↑, 1,  

Migration ⓘ

Ca+2↑, 1,   CDKN1C↑, 1,   CLDN1↓, 1,   E-cadherin↑, 1,   MMP2↓, 1,   MMP9↓, 1,   TumCMig↓, 1,   Twist↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   VitD↑, 1,  

Hormonal & Nuclear Receptors ⓘ

DHT↑, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,   Dose↝, 1,   eff↑, 3,   selectivity↑, 2,  

Clinical Biomarkers ⓘ

GutMicro↝, 1,   hTERT/TERT↓, 1,   VitD↑, 1,  

Functional Outcomes ⓘ

neuroP↑, 1,   OS↑, 1,   TumVol↓, 1,  
Total Targets: 35

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 3,   Catalase↑, 2,   GPx↑, 2,   GSH↑, 1,   GSTs↑, 1,   HDL↑, 6,   HDL∅, 1,   lipid-P↓, 2,   MDA↓, 1,   ROS↓, 3,   SOD↑, 3,   VitC↑, 1,  

Core Metabolism/Glycolysis ⓘ

adiP↓, 1,   ALAT↓, 1,   glucose↓, 1,   LDL↓, 6,  

Cell Death ⓘ

MAPK↓, 1,  

Transcription & Epigenetics ⓘ

other↑, 2,   other↝, 1,   other∅, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1↑, 1,   IGFBP1↑, 1,   PTEN↑, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,   VEGF↑, 1,  

Immune & Inflammatory Signaling ⓘ

CRP↓, 1,   IL1β↓, 2,   IL6↓, 2,   Inflam↓, 3,   NF-kB↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioEnh↑, 2,   Dose↝, 3,   eff↓, 3,   eff↑, 2,   eff↝, 1,   Half-Life↑, 1,   P450↓, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   BP↓, 1,   CRP↓, 1,   GutMicro↑, 1,   IL6↓, 2,  

Functional Outcomes ⓘ

AntiAge↑, 1,   BOLD↑, 1,   cardioP↑, 3,   cognitive↑, 2,   hepatoP↑, 1,   memory↑, 1,   neuroP↑, 2,   Obesity↓, 1,   QoL↑, 1,   RenoP↑, 1,   Risk↓, 3,   toxicity↝, 1,  
Total Targets: 60

Scientific Paper Hit Count for: HDL, HDL cholesterol
2 Selenium
1 Anthocyanins
1 Boron
1 Chrysin
1 Coenzyme Q10
1 Ellagic acid
1 Lecithin
1 Vitamin B5,Pantothenic Acid
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:63  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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