Database Query Results : , , miR-125b

miR-125b, miR-125b: Click to Expand ⟱
Source:
Type:
miRNA-125b is a microRNA that has been extensively studied in the context of cancer. MicroRNAs (miRNAs) are small non-coding RNAs that play a crucial role in regulating gene expression by binding to the 3' untranslated region (3' UTR) of target mRNAs, leading to their degradation or inhibition of translation.

miRNA-125b has been found to be involved in various types of cancer, including leukemia, breast cancer, lung cancer, and ovarian cancer. Its role in cancer is complex and can be either oncogenic (cancer-promoting) or tumor-suppressive, depending on the type of cancer and the cellular context.

miR-125b is generally upregulated in various cancers, and its high expression is often associated with poor prognosis and protumorigenic effects.
miR-125b regulates programs central to cell fate:
-Apoptosis and survival
-Differentiation vs stemness
-Cell-cycle progression
-Stress and inflammatory signaling


Scientific Papers found: Click to Expand⟱
402- SNP,  MF,    Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study
- in-vitro, BC, MCF-7
P53↑, iNOS↑, NF-kB↑, Bcl-2↓, miR-125b↓, ROS↑, SOD↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,   SOD↑, 1,  

Cell Death ⓘ

Bcl-2↓, 1,   iNOS↑, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

miR-125b↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↑, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-125b, miR-125b
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:636  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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