Database Query Results : , , autolysosome

autolysosome, autolysosome: Click to Expand ⟱
Source:
Type:
Autolysosomes are organelles involved in the process of autophagy, a cellular mechanism that degrades and recycles damaged or dysfunctional cellular components.
Autolysosomes, specifically, are involved in the final stages of autophagy, where the autophagosome fuses with a lysosome to form an autolysosome. The autolysosome then degrades the engulfed cellular components, releasing the resulting nutrients back into the cell.
Scientific Papers found: Click to Expand⟱
404- CUR,    Curcumin induces ferroptosis in non-small-cell lung cancer via activating autophagy
- vitro+vivo, Lung, A549 - vitro+vivo, Lung, H1299
TumAuto↑, TumCG↓, TumCP↓, Iron↑, GSH↓, lipid-P↑, GPx↓, mtDam↑, autolysosome↑, Beclin-1↑, LC3s↑, p62↓, Ferroptosis↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   GPx↓, 1,   GSH↓, 1,   Iron↑, 1,   lipid-P↑, 1,  

Mitochondria & Bioenergetics ⓘ

mtDam↑, 1,  

Cell Death ⓘ

Ferroptosis↑, 1,  

Autophagy & Lysosomes ⓘ

autolysosome↑, 1,   Beclin-1↑, 1,   LC3s↑, 1,   p62↓, 1,   TumAuto↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,  

Migration ⓘ

TumCP↓, 1,  
Total Targets: 14

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: autolysosome, autolysosome
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:637  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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