Database Query Results : , , BACH1

BACH1, BTB and CNC homology 1: Click to Expand ⟱
Source:
Type:
Bach1 (BTB and CNC homology 1) is a protein involved in the regulation of gene expression, specifically through the control of the stability and translation of messenger RNA (mRNA).
Bach1 has been found to be overexpressed in several types of cancer, including lung, breast, and prostate cancer. High levels of Bach1 have been associated with increased cancer cell proliferation, migration, and invasion, as well as reduced sensitivity to chemotherapy.
Scientific Papers found: Click to Expand⟱
414- CUR,    Transcriptome Investigation and In Vitro Verification of Curcumin-Induced HO-1 as a Feature of Ferroptosis in Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
Ferroptosis↑, Iron↑, ROS↑, lipid-P↑, MDA↑, GSH↓, HO-1↑, NRF2↑, GPx↓, ROS↑, Iron↑, GPx4↓, HSP70/HSPA5↑, ATFs↑, CHOP↑, MDA↑, FTL↑, FTH1↑, BACH1↑, REL↑, USF1↑, NFE2L2↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   GPx↓, 1,   GPx4↓, 1,   GSH↓, 1,   HO-1↑, 1,   Iron↑, 2,   lipid-P↑, 1,   MDA↑, 2,   NFE2L2↑, 1,   NRF2↑, 1,   ROS↑, 2,  

Metal & Cofactor Biology ⓘ

FTH1↑, 1,   FTL↑, 1,  

Cell Death ⓘ

Ferroptosis↑, 1,  

Transcription & Epigenetics ⓘ

USF1↑, 1,  

Protein Folding & ER Stress ⓘ

ATFs↑, 1,   CHOP↑, 1,   HSP70/HSPA5↑, 1,  

Migration ⓘ

BACH1↑, 1,  

Angiogenesis & Vasculature ⓘ

REL↑, 1,  
Total Targets: 20

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: BACH1, BTB and CNC homology 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:647  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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