Database Query Results : , , Albumin

Albumin, Albumin: Click to Expand ⟱
Source:
Type: protein
Albumin is a protein found in the blood that plays a crucial role in maintaining various bodily functions, including blood volume, blood pressure, and the transport of hormones, vitamins, and minerals.
Associated with improved prognosis in certain types of cancer.
May be a marker of improved nutritional status and reduced inflammation in cancer patients.
Albumin is the most abundant plasma protein, synthesized by the liver. Biologically, it maintains oncotic pressure, transports hormones/drugs, and buffers redox and metabolic stress.

In oncology, serum albumin is a host-state biomarker, not a tumor marker.

What Low Albumin Means in Cancer
-Hypoalbuminemia reflects a convergence of cancer-relevant processes:
-Chronic inflammation (IL-6 suppresses hepatic albumin synthesis)
-Catabolism and cachexia
-Poor nutritional reserve
-Liver synthetic stress
-Advanced systemic disease

Low albumin is therefore a global severity signal, not a single-pathway readout.


Scientific Papers found: Click to Expand⟱
438- CUR,    Curcumin Reduces Colorectal Cancer Cell Proliferation and Migration and Slows In Vivo Growth of Liver Metastases in Rats
- vitro+vivo, CRC, CC531
TumCP↓, TumVol↓, Albumin↑, ALP↑, AST↑, ALAT↑, cholinesterase↓,
4445- Se,  DFE,    A comparative study on the hepatoprotective effect of selenium-nanoparticles and dates flesh extract on carbon tetrachloride induced liver damage in albino rats
- in-vivo, LiverDam, NA
*hepatoP↑, *antiOx↑, *AntiCan↑, *BioAv↑, *toxicity↓, *ROS↓, *MDA↓, *ALAT↓, *Albumin↑, *GSH↑, *SOD↑, *RenoP↑,
2276- VitK2,    Vitamin K2 (MK-7) Intercepts Keap-1/Nrf-2/HO-1 Pathway and Hinders Inflammatory/Apoptotic Signaling and Liver Aging in Naturally Aging Rat
- in-vivo, Nor, NA
*Albumin↑, *AST↓, *ALAT↓, *Keap1↓, *NRF2↑, *HO-1↑, *COX2↓, *iNOS↓, *TNF-α↓, *TIMP1↓, *TGF-β↓, *ROS↓, *DNAdam↓, *Inflam↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

ALAT↑, 1,  

Migration ⓘ

TumCP↓, 1,  

Synaptic & Neurotransmission ⓘ

cholinesterase↓, 1,  

Clinical Biomarkers ⓘ

ALAT↑, 1,   Albumin↑, 1,   ALP↑, 1,   AST↑, 1,  

Functional Outcomes ⓘ

TumVol↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   GSH↑, 1,   HO-1↑, 1,   Keap1↓, 1,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 2,   SOD↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 2,  

Cell Death ⓘ

iNOS↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Migration ⓘ

TGF-β↓, 1,   TIMP1↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   Inflam↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 2,   Albumin↑, 2,   AST↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   hepatoP↑, 1,   RenoP↑, 1,   toxicity↓, 1,  
Total Targets: 24

Scientific Paper Hit Count for: Albumin, Albumin
1 Curcumin
1 Selenium
1 Date Fruit Extract
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:690  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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