Database Query Results : , , StAR

StAR, Steroidogenic Acute Regulatory protein: Click to Expand ⟱
Source:
Type: protein
StAR (Steroidogenic Acute Regulatory protein) is a protein that plays a crucial role in the regulation of steroid hormone biosynthesis. It is involved in the transfer of cholesterol into the mitochondria, where it is converted into pregnenolone, the precursor to all steroid hormones.

StAR is overexpressed in various types of cancer, including breast, prostate, and ovarian cancer. This overexpression is often associated with increased steroid hormone production, which can promote tumor growth and progression.
Scientific Papers found: Click to Expand⟱
131- CUR,    Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer
- vitro+vivo, Pca, LNCaP - vitro+vivo, Pca, 22Rv1
AKR1C2↓, CYP11A1↓, HSD3B↓, DHT↓, testos↓, StAR↓, SRD5A1↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Migration ⓘ

AKR1C2↓, 1,  

Hormonal & Nuclear Receptors ⓘ

CYP11A1↓, 1,   DHT↓, 1,   HSD3B↓, 1,   SRD5A1↑, 1,   StAR↓, 1,   testos↓, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: StAR, Steroidogenic Acute Regulatory protein
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:731  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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