Database Query Results : , , SRD5A1

SRD5A1, SRD5A1: Click to Expand ⟱
Source:
Type: gene
SRD5A1 is a gene that encodes the enzyme 5-alpha-reductase type 1. This enzyme plays a crucial role in the conversion of testosterone to dihydrotestosterone (DHT), a potent androgen hormone.
Elevated Expression in: prostate, breast, ovarian, endometrial, adrenal, testcular, uterine, adenocarcinoma.
Scientific Papers found: Click to Expand⟱
131- CUR,    Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer
- vitro+vivo, Pca, LNCaP - vitro+vivo, Pca, 22Rv1
AKR1C2↓, CYP11A1↓, HSD3B↓, DHT↓, testos↓, StAR↓, SRD5A1↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Migration ⓘ

AKR1C2↓, 1,  

Hormonal & Nuclear Receptors ⓘ

CYP11A1↓, 1,   DHT↓, 1,   HSD3B↓, 1,   SRD5A1↑, 1,   StAR↓, 1,   testos↓, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: SRD5A1, SRD5A1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:732  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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