Database Query Results : , , PLEKHM3

PLEKHM3, PLEKHM3: Click to Expand ⟱
Source:
Type:
PLEKHM3 is a protein-coding gene that has been associated with various types of cancer. The PLEKHM3 gene encodes a protein that is involved in the regulation of cell growth, division, and survival.

Research has shown that PLEKHM3 is overexpressed in several types of cancer, including breast cancer, lung cancer, and colon cancer. Overexpression of PLEKHM3 has been linked to increased cell proliferation, tumor growth, and metastasis.
Scientific Papers found: Click to Expand⟱
472- CUR,    Curcumin inhibits ovarian cancer progression by regulating circ-PLEKHM3/miR-320a/SMG1 axis
- vitro+vivo, Ovarian, SKOV3 - vitro+vivo, Ovarian, A2780S
TumCP↓, Apoptosis↑, PCNA↓, miR-320a↓, BAX↑, cl‑Casp3↑, circ‑PLEKHM3↑, SMG1↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Apoptosis↑, 1,   BAX↑, 1,   cl‑Casp3↑, 1,  

DNA Damage & Repair ⓘ

PCNA↓, 1,   SMG1↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

circ‑PLEKHM3↑, 1,  

Migration ⓘ

miR-320a↓, 1,   TumCP↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: PLEKHM3, PLEKHM3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:747  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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