Database Query Results : , , miR-126

miR-126, miR-126: Click to Expand ⟱
Source:
Type: tumour-suppressor miRNA
miR-126 is involved in the regulation of angiogenesis, which is the process of forming new blood vessels.
miR-126 is downregulated in many types of cancer, including breast, lung, colon, and pancreatic cancer.
The downregulation of miR-126 has been associated with poor prognosis and increased metastasis in cancer patients.
Scientific Papers found: Click to Expand⟱
736- Bor,    Evaluation of Boric Acid Treatment on microRNA-127-5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells
- in-vitro, BC, MCF-7
miR-126↑, COL1A1↓, Vim↓, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑, miR-127-5p↑,
4707- CUR,    The Potential Role of Curcumin as a Regulator of microRNA in Colorectal Cancer: A Systematic Review
- Review, Var, NA
miR-497↑, miR-200c↑, miR-409-3p↑, miR-34a↑, miR-126↑, miR-145↑, miR-206↑, miR-491↑, miR-141↑, miR-429↑, miR-101↑, miR-15↑, miR-21↓, miR-155↓, miR-221↓, miR‐222↓, miR-17↓, miR-130a↓, miR-27a-3p↓, miR-20↓,
522- MF,    Low Magnetic Field Exposure Alters Prostate Cancer Cell Properties
- in-vitro, Pca, PC3
MMP2↑, MMP9↑, miR-21↑, miR-155↑, miR-210↑, miR-200c↓, miR-126↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

miR-127-5p↑, 1,   miR-497↑, 1,  

Transcription & Epigenetics ⓘ

miR-145↑, 1,   miR-21↓, 1,   miR-21↑, 1,   miR-27a-3p↓, 1,   miR-409-3p↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

miR-101↑, 1,   miR-34a↑, 1,   miR-429↑, 1,  

Migration ⓘ

CDH1↑, 1,   COL1A1↓, 1,   ITGA5↑, 1,   ITGB1↑, 1,   LAMA5↑, 1,   miR-130a↓, 1,   miR-141↑, 1,   miR-155↓, 1,   miR-155↑, 1,   miR-20↓, 1,   miR-200c↓, 1,   miR-200c↑, 1,   miR-206↑, 1,   miR-221↓, 1,   miR-491↑, 1,   miR‐222↓, 1,   MMP2↑, 1,   MMP9↑, 1,   Snail↑, 1,   Vim↓, 1,   Zeb1↑, 1,  

Angiogenesis & Vasculature ⓘ

miR-126↓, 1,   miR-126↑, 2,   miR-15↑, 1,   miR-17↓, 1,   miR-210↑, 1,  
Total Targets: 36

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-126, miR-126
1 Boron
1 Curcumin
1 Magnetic Fields
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:766  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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