| Source: CGL-Driver Genes |
| Type: Oncogene |
| Anaplastic lymphoma kinase (ALK) is a member of the insulin receptor protein-tyrosine kinase superfamily. ALK inhibitors, has substantially improved outcomes for patients with ALK-positive NSCLC. The common activation of ALK has led to the use of the ALK tyrosine kinase inhibitor (TKI) crizotinib. ALK is used as a clinical biomarker for Fusion targeted therapy |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:8 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid