Database Query Results : , , RHBDD1

RHBDD1, Rhomboid Domain Containing 1: Click to Expand ⟱
Source:
Type:
RHBDD1 encodes a member of the rhomboid family of intramembrane serine proteases. Although the precise functions of RHBDD1 are still being elucidated, emerging evidence suggests that it may influence several cancer-related processes including cell proliferation, apoptosis, and migration. Its enzymatic role within the cell, particularly in the modulation of signaling pathways through regulated proteolysis, is thought to contribute to changes in the tumor microenvironment and tumor progression.

In certain cancer types—such as colorectal, hepatocellular, or breast cancers—RHBDD1 expression has been found to be upregulated.
The increased expression of RHBDD1 in tumors suggests that it may contribute to oncogenic transformation or progression.
Higher levels of RHBDD1 expression have been associated with increased tumor proliferation and poorer survival rates in some cancers.

RHBDD1 holds promise both as a prognostic biomarker and as a potential therapeutic target.
Scientific Papers found: Click to Expand⟱
1127- SIL,    Silibinin suppresses epithelial–mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1
- in-vitro, Lung, A549
TumCP↓, TumCMig↓, TumCI↓, EMT↓, RHBDD1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,  

Migration ⓘ

RHBDD1↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: RHBDD1, Rhomboid Domain Containing 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:817  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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