Database Query Results : , , CTR1

CTR1, Copper Transporter 1: Click to Expand ⟱
Source:
Type:
CTR1 (Copper Transporter 1) is a protein that plays a crucial role in the transport of copper into cells. Copper is an essential nutrient that is required for various cellular processes, including the regulation of cell growth, differentiation, and survival.
CTR1 has been found to be overexpressed in various types of tumors, including breast, lung, colon, and prostate cancer. The overexpression of CTR1 in cancer cells has been linked to increased copper uptake, which can promote tumor growth and progression.
Scientific Papers found: Click to Expand⟱
692- EGCG,    EGCG: The antioxidant powerhouse in lung cancer management and chemotherapy enhancement
- Review, NA, NA
ROS↑, Apoptosis↑, DNAdam↑, CTR1↑, JWA↑, β-catenin/ZEB1↓, P53↑, Vim↓, VEGF↓, p‑Akt↓, Hif1a↓, COX2↓, ERK↓, NF-kB↓, Akt↓, Bcl-xL↓, miR-210↓,
4383- SNP,    Exploring the Potentials of Silver Nanoparticles in Overcoming Cisplatin Resistance in Lung Adenocarcinoma: Insights from Proteomic and Xenograft Mice Studies
- in-vitro, Lung, A549 - in-vivo, Lung, A549
Apoptosis↑, VEGF↓, P53↓, TumCCA↑, ROS↑, AntiTum↑, eff↑, ATP↓, eff↑, CTR1↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 2,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,  

Cell Death ⓘ

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↑, 2,   Bcl-xL↓, 1,   JWA↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   P53↓, 1,   P53↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,  

Migration ⓘ

Vim↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↓, 1,   miR-210↓, 1,   VEGF↓, 2,  

Barriers & Transport ⓘ

CTR1↑, 2,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 2,  

Functional Outcomes ⓘ

AntiTum↑, 1,  
Total Targets: 22

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CTR1, Copper Transporter 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:844  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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