Database Query Results : , , sFasL

sFasL, soluble Fas Ligand: Click to Expand ⟱
Source:
Type:
sFasL (soluble Fas Ligand) is a protein that plays a crucial role in the regulation of apoptosis (programmed cell death) and immune responses.
sFasL has been shown to promote tumor growth, invasion, and metastasis by regulating the expression of genes involved in cell proliferation, survival, and migration.
sFasL has been found to be highly expressed in cancer stem cells.
Scientific Papers found: Click to Expand⟱
741- Bor,    Boron Derivatives Inhibit the Proliferation of Breast Cancer Cells and Affect Tumor-Specific T Cell Activity In Vitro by Distinct Mechanisms
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
MOB1↓, PD-L1↑, p‑YAP/TEAD↝, IFN-γ↓, sFasL↑, Perforin↓, GranA↓, GranB↓, GNLY↓, PD-1↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

GranA↓, 1,   GranB↓, 1,   Perforin↓, 1,   sFasL↑, 1,   p‑YAP/TEAD↝, 1,  

Migration ⓘ

MOB1↓, 1,  

Immune & Inflammatory Signaling ⓘ

GNLY↓, 1,   IFN-γ↓, 1,   PD-1↑, 1,   PD-L1↑, 1,  

Clinical Biomarkers ⓘ

PD-L1↑, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: sFasL, soluble Fas Ligand
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:869  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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