Database Query Results : , , H3K18

H3K18, Histone 3 Lysine 18: Click to Expand ⟱
Source:
Type:
H3K18 (Histone 3 Lysine 18) is a histone modification that has been implicated in various types of cancer. Histone modifications play a crucial role in regulating gene expression, and H3K18 is one of the most well-studied histone modifications.
H3K18 has been found to be overexpressed in various types of cancer, including breast, prostate, lung, and colon cancer.
Targeting H3K18 with small molecule inhibitors has been shown to be a promising therapeutic strategy for cancer treatment.
Scientific Papers found: Click to Expand⟱
797- GAR,  CUR,    Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells
- in-vitro, BC, MCF-7 - in-vitro, OS, U2OS - in-vitro, OS, SaOS2
TumCP↓, H3K18↓, DNAdam↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Kinase & Signal Transduction ⓘ

H3K18↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,  

Migration ⓘ

TumCP↓, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: H3K18, Histone 3 Lysine 18
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:889  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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