Database Query Results : , , pS2/TFF1

pS2/TFF1, pS2/TFF1: Click to Expand ⟱
Source:
Type:
pS2 (also known as TFF1) is a protein that is involved in various cellular processes, including cell growth, differentiation, and survival. In the context of cancer, pS2 has been implicated in several types of cancer, including breast, ovarian, endometrial, prostate, lung, and colorectal cancer.

-Tumor suppressor: pS2 has been shown to have tumor suppressor properties, as it can inhibit cell growth and induce apoptosis (cell death) in cancer cells.
-Hormone regulation: pS2 is a progesterone-induced gene, and its expression is regulated by hormonal changes. In cancer, pS2 expression can be influenced by hormonal imbalances, leading to changes in tumor growth and behavior.
-Cell adhesion and migration: pS2 has been shown to regulate cell adhesion and migration, which are critical processes in cancer metastasis.
-Angiogenesis: pS2 has been implicated in the regulation of angiogenesis, the process of new blood vessel formation, which is essential for tumor growth and metastasis.


pS2 is often downregulated in various types of cancer, including breast, ovarian, endometrial, prostate, lung, and colorectal cancer.
Scientific Papers found: Click to Expand⟱
984- Sel,    Effects of selenite on estrogen receptor-alpha expression and activity in MCF-7 breast cancer cells
- in-vitro, BC, MCF-7
ERα/ESR1↓, PR↑, pS2/TFF1↑, Catalase↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↑, 1,  

Cell Death ⓘ

pS2/TFF1↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

PR↑, 1,  

Hormonal & Nuclear Receptors ⓘ

ERα/ESR1↓, 1,  

Clinical Biomarkers ⓘ

ERα/ESR1↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: pS2/TFF1, pS2/TFF1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:939  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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