Database Query Results : , , ACOX1

ACOX1, Acyl-CoA Oxidase 1: Click to Expand ⟱
Source:
Type:
ACOX1 (Acyl-CoA Oxidase 1) is an enzyme that plays a crucial role in the regulation of fatty acid metabolism, particularly in the breakdown of fatty acids in peroxisomes.

ACOX1 is typically overexpressed and is associated with poor prognosis and reduced overall survival in breast, lung, and colon cancers.
-ACOX1 expression is also associated with increased risk of metastasis and recurrence in various types of cancer.
Scientific Papers found: Click to Expand⟱
1006- CUR,    The effect of Curcuma longa extract and its active component (curcumin) on gene expression profiles of lipid metabolism pathway in liver cancer cell line (HepG2)
- in-vitro, Liver, HepG2
TumCP↓, PGC1A↑, CPT1A↑, ACOX1↑, SCD1↓, SREBF2↓, DGAT1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

ACOX1↑, 1,   CPT1A↑, 1,   DGAT1↓, 1,   PGC1A↑, 1,   SCD1↓, 1,   SREBF2↓, 1,  

Migration ⓘ

TumCP↓, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: ACOX1, Acyl-CoA Oxidase 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:957  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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